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Slow Cooker Sante Fe Meatloaf

This Slow Cooker Sante Fe Meatloaf recipe is a fantastic way to get a delicious meal on the table without all the stress!

Course Entree
Cuisine American
Keyword meatloaf, slow cooker meatloaf, slow cooker sante fe meatloaf
Prep Time 15 minutes
Cook Time 4 hours 45 minutes
Resting Time 15 minutes
Total Time 5 hours 15 minutes
Servings 10
Calories 320kcal
Author Trish - Mom On Timeout


  • 2 tbsp olive oil
  • 1 cup onion diced
  • 1 cup red bell pepper diced
  • 5 garlic cloves minced
  • 1 tbsp tomato paste
  • 1/2 tsp cumin
  • 1 tsp dried oregano
  • 1/2 tbsp chili powder
  • 15 oz black beans 1 can - rinsed and drained
  • 3 slices white or wheat if that's what you have on hand sandwich bread, torn into small pieces
  • 1/2 cup milk
  • 2 lbs lean ground beef
  • 1 cup Mexican blend shredded cheese
  • 3/4 cup frozen corn
  • 2 large eggs lightly beaten
  • 2 oz diced green chiles half of 4 oz can
  • 2 tbsp fresh cilantro chopped
  • 1 tsp salt
  • 1/2 tsp pepper
  • 1/2 cup barbeque sauce divided


  • Line slow cooker with foil collar and sling. Spray with cooking spray.
  • Saute onion and bell pepper in vegetable oil for 3-4 minutes. Add garlic and continue cooking for 1-2 more minutes.
  • Stir in tomato paste, cumin, oregano and chili powder and continue cooking for 2 minutes more.
  • Mash bread, beans, and milk together in a large bowl using your hands.
  • Combine bread mixture and onion mixture with ground beef, cheese, corn, eggs, green chiles, cilantro, salt and pepper using your hands.
  • Press mixture into an even layer in slow cooker.
  • Brush with 1/4 cup of barbecue sauce.
  • Cover and cook on low for 4 hours or until meatloaf is tender and cooked through.
  • Heat broiler. Transfer meatloaf, using foil sling, to a rimmed baking sheet. Let juices drain into the slow cooker.
  • Push foil away from meatloaf and brush with remaining 1/4 cup barbeque sauce.
  • Broil for 3-5 minutes until sauce is bubbling and beginning to caramelize.
  • Let meatloaf rest for 15 minutes before serving.


Calories: 320kcal | Carbohydrates: 23g | Protein: 28g | Fat: 12g | Saturated Fat: 5g | Cholesterol: 101mg | Sodium: 558mg | Potassium: 668mg | Fiber: 5g | Sugar: 7g | Vitamin A: 795IU | Vitamin C: 23mg | Calcium: 129mg | Iron: 4mg